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A mutant (M45) of the cyanobacterium Synechococcus sp. Strain PCC 7942, which is defective in active transport of nitrate, was used for the studies of the nitrogen regulation of the genes involved in nitrate and CO2 assimilation. In a medium containing 30 mM nitrate as the nitrogen source, M45 grew under constant stress of nitrogen deficiency and accumulated a five-times-larger amount of the transcript of nirA, the gene for nitrite reductase, compared with nitrate-grown wild-type cells. Questionnaires containing variables of interest were administered to women during their last trimester; infant feeding method was assessed at 1 week and 4 months postpartum. Intended breastfeeding duration and breastfeeding self-efficacy were identified as the most significant modifiable variables predictive of breastfeeding outcomes. Mothers who intended to breastfeed for < 6 months were 2.4 times as likely to have discontinued breastfeeding at 4 months compared to those who intended to breastfeed for > 12 months (35.7% vs 87.5%). In fifteen patients, a subtle injury of the Lisfranc joint (tarsometatarsal articulation) was found. The lesion was defined as a diastasis of two to five millimeters between the bases of the first and second metatarsals, as seen on anteroposterior radiographs. There often was a long delay between injury and diagnosis. BACKGROUND: Recent trials demonstrate the acceptability and short term efficacy of primary care referral to a commercial weight loss provider for weight management. Commissioners now need information on the optimal duration of intervention and the longer term outcomes and cost effectiveness of such treatment to give best value for money.METHODS/DESIGN: This multicentre, randomised controlled trial with a parallel design will recruit 1200 overweight adults (BMI ≥28 kg/m2) through their primary care provider. They will be randomised in a 2:5:5 allocation to: Brief Intervention, Commercial Programme for 12 weeks, or Commercial Programme for 52 weeks. Workflows can be created on traditional computing clusters as well as cloud-based services.AVAILABILITY AND IMPLEMENTATION: Source code is available for academic Nike Air Huarache non-commercial research purposes. Links to code and documentation are provided at Nike Air Max 1 Dublin and or INFORMATION: Supplementary data are available at Bioinformatics online.© The Author 2014. Published by Oxford University Press..  


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